How Does Avandra 100mg Tablet Work to Treat ED?

Erectile dysfunction (ED) can affect men across the lifespan, making it a prevalent sensual condition. It manifests as the inability to achieve or maintain an erection suitable for sensual intercourse. Amidst the array of treatment options accessible for ED, the Avandra 100 tablet has emerged as a highly effective and favored choice among individuals seeking a solution to this common concern. See below the mechanics of how the Avandra 100 tablet works to treat ED.


What is Avandra 100

Avandra 100 is a medication commonly prescribed to treat erectile dysfunction. Its active ingredient is Avanafil 100mg, a phosphodiesterase type 5 (PDE-5) inhibitor. Avanafil works by addressing the physiological factors that contribute to ED, particularly those related to blood flow and the relaxation of smooth muscle in the genital part.


Mechanism of Action

  • To understand how Avandra 100mg tablet works, we must first examine the physiological process that leads to an erection. Sensual stimulation triggers the release of nitric oxide (NO) in the genital part. NO is a chemical messenger that relaxes the smooth muscle cells lining the blood vessels in the corpora cavernosa (two chambers in the genital part). This relaxation allows blood to flow into the genital part, engorging it and resulting in an erection.
  • In men with ED, there is often an overproduction of another enzyme called phosphodiesterase type 5 (PDE-5). PDE-5 breaks down cGMP (cyclic guanosine monophosphate), a molecule that maintains the smooth muscle relaxation required for an erection. Avandra 100mg tablet contains sildenafil citrate, which is a PDE-5 inhibitor. When this medication is taken, it works by inhibiting the action of PDE-5, allowing cGMP levels to increase and thus promoting the relaxation of smooth muscle in the genital part.
  • As cGMP levels rise due to PDE-5 inhibition, the smooth muscle in the penile blood vessels relaxes further. This relaxation leads to an increased flow of blood into the corpora cavernosa, resulting in a firm and sustainable erection. It's important to note that Avandra 100mg tablet does not directly cause an erection; rather, it facilitates the natural processes that lead to one when sensual arousal is present.
  • The effects of Avanafil 100mg typically last for about 4-6 hours. This gives the user a window of time during which they can achieve and maintain an erection in response to sensual stimulation.


Factors Affecting Avandra's Efficacy

The effectiveness of Avandra 100mg tablet can vary from person to person, and several factors can influence how well it works. These factors include: 

  • Avandra 100 is most effective for ED caused by vascular issues or PDE-5 overactivity. It may be less effective if ED is primarily due to psychological factors or hormonal imbalances.
  • It's important to take Avandra 100 about 30 minutes to an hour before sensual activity for optimal results. Food can affect the absorption rate, so taking it on an empty stomach may lead to a faster onset of action.
  • The prescribed dosage is crucial. A healthcare provider will determine the appropriate dosage based on an individual's medical history and the severity of their ED.
  • Certain health conditions and lifestyle choices, such as obesity, diabetes, or excessive alcohol consumption, can impact Avandra's efficacy.
  • Psychological factors like anxiety and stress can interfere with sensual arousal, potentially affecting the medication's effectiveness. 



Avandra 100mg tablet, with its active ingredient Avanafil 100mg, has revolutionized the treatment of erectile dysfunction. By targeting the physiological processes involved in achieving and maintaining an erection, it has provided millions of men with a reliable and effective solution to this common issue.

However, it's essential to remember that Avandra 100 is not a cure for ED. It addresses the symptoms and facilitates the natural processes that lead to an erection when sensual arousal is present. Additionally, like all medications, Avandra may have side effects and interactions with other drugs, so it should only be used under the guidance of a healthcare professional.

If you or someone you know is struggling with ED, seeking the advice of a healthcare provider is the first step toward finding the most suitable treatment. Avandra 100mg tablet, when used correctly, can be a valuable tool in regaining confidence and intimacy in one's life.